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The Best Stain Removers to Keep Your Clothes Clean

Buyer's Report GUIDE Team
Written By Buyer's Report GUIDE Team
Last updated: May 8, 2025, 01:39 PM
Affiliate Disclosure ↓

Stain happens! Everyone has to prepare themselves for this. The only solution to get rid of stains in clothing is to get the best stain remover possible. Stain removers will act as a solvent for water-based and oil stains. You will see different kinds of stain removers in the market, but the selection has to be done per individual needs. Want to buy the best stain removers in 2025? Consider purchasing the below products.

View all Contents
  • Top Stain Removers Buying Guide
    • What Are Two Different Types of Stain Removers?
    • What Are Different Types of Stain Removing Solvents?
    • What Key Things to Consider When Buying Stain Removers?
    • How to Remove Stains From Clothes:
  • Stain Remover FAQs
  • Elevating the Shopping Game
  • Contributors

Our Top Picks

  • Emergency Stain Rescue Stain Remover: Best Overall (Shop Now) →
    Read more about this best stain remover ↓
  • Tide To Go Instant Stain Remover: Best in Premium Quality (Shop Now) →
    Read more about this best stain remover ↓
  • Puracy Laundry Stain Remover: Best Buy (Shop Now) →
    Read more about this best stain remover ↓
  • Biokleen Natural Stain Remover: Most Eco-Friendly (Shop Now) →
    Read more about this best stain remover ↓
  • OxiClean Stain Remover Spray: Also Consider (Shop Now) →
    Read more about this best stain remover ↓
  • Dreft 24 Ounces Stain Remover: Best in Affordability (Shop Now) →
    Read more about this best stain remover ↓

Leading Stain Remover in 2025 Reviewed

Emergency Stain Rescue Stain Remover

Best Overall
Check On Amazon

The Emergency Stain Rescue stain remover effectively removes even the toughest of stains. This professional-grade formula is safe for kids and pets and works on organic and inorganic matter. This universal spot remover is free of harsh chemicals like peroxide, chlorine, phosphates, perfumes, or dyes. 

Its pH-neutral formula is tough on stains but not on skin and fabric. Additionally, it’s fast-acting and can be used as a stain stick alternative or with cleaner wipes (sold separately) when traveling. This stain remover can easily eliminate stubborn coffee, baby formula, ketchup, and pet stains, making this versatile product the top choice on our list.

What Travelers Love
  • Safe for kids, pets, and fabrics

  • Free from harsh chemicals and perfumes

  • Fast-acting for tough stain removal

What to Note
  • Requires separate cleaner wipes for travel

Key features/specs
Has a fast-acting formula that quickly removes even the toughest stains
This product is versatile and can be used on a wide range of stains, including food, grease, oil, and even pet stains
It is safe for all fabrics, including delicate fabrics like silk and wool
This stain remover is easy to use and doesn’t require any special equipment or tools
This product is environmentally friendly and doesn’t contain any harsh chemicals

Tide To Go Instant Stain Remover

Best in Premium Quality
Check On Amazon

This quick stain remover pen will help you get rid of the tough grease stain on the go. It has a powerful cleaning solution that will break the stain down and a microfiber pad to lift and absorb them. Moreover, this is very effective in removing the harsh drink and fresh food stain with great ease.

What Travelers Love
  • Quick and portable for on-the-go use

  • Powerful solution breaks down tough stains

  • Includes microfiber pad for easy cleaning

What to Note
  • May not work on set-in stains

Key features/specs
Effectively works against different stains like BBQ, sauce, ketchup, and much more
Resembles the shape of a pen; it is small and easy to handle
No bleach inside, so no worries about damage or discoloration
Very easy to use. Just remove the excess residue, press the tip on the stain and rub it gently for stain removal

Puracy Laundry Stain Remover

Best Buy
Check On Amazon

All six-plant based enzymes power it for efficiently removing the stain from fabrics. Enzymes are safe and very effective in eliminating odors, residues, and spots without the need for bleach. Since there is no bleach, you don’t have to worry about damaging the fabric or discoloration. As the product is plant-based, there are no harsh chemicals inside.

What Travelers Love
  • Powered by six plant-based enzymes

  • Safe for fabrics without bleach or chemicals

  • Effectively eliminates odors, residues, and spots

What to Note
  • May not work on all types of stains

Key features/specs
It is child, pet, and environment friendly; hypoallergenic, and non-toxic
Plant-based enzymes will remove the stain
No use of ammonia, sulfates, petrochemicals, or bleach present
Can be used for cleaning floor mats, car seats, cloth diapers, dress shirts, bedding, and much more

Biokleen Natural Stain Remover

Most Eco-Friendly
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A unique blend of plant-powered substances uses live enzymes for removing the tough odors and stains. It works great on laundry, clothes, furniture, carpets, and much more. The enzyme culture present will break the odors and stain into tiny particles. There are no harsh chemicals, so you can easily use them to remove stains from your child or pet’s area.

What Travelers Love
  • Uses plant-powered enzymes for effective cleaning

  • Safe for laundry, furniture, and carpets

  • No harsh chemicals, safe for children

What to Note
  • May require multiple applications for tough stains

Key features/specs
The BioActive formula uses natural plant-based enzymes to provide maximum cleaning
There is no chlorine, ammonia, phosphates, artificial colors, or artificial fragrance
It is a referable choice of commercial carpet cleaners
People who have sensitivity to chemicals or any allergies can use it as no harsh chemicals are present

OxiClean Stain Remover Spray

Also Consider
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It is available in a sprayer bottle for easy application and is very effective in removing five different stains: grease/oil, grass/blood, food, drink, and soil/clay. This formula will work in all water temperatures and even on dried clothes. It is effortless to use because you have to spray the solution on the affected area and rub it to see the magic.

What Travelers Love
  • Effective on five different types of stains

  • Works in all water temperatures

  • Easy to apply with a spray bottle

What to Note
  • Requires rubbing for optimal results

Key features/specs
Conveniently remove the stain in 5 to 10 minutes. Afterward, you can wash it
It has a chlorine-free formula which makes it best for regular use without the worry of discoloration
Helps fight the toughest stain on your wet or dry clothes
Can remove stains from several items like clothes, bedsheets, carpets, etc.

Dreft 24 Ounces Stain Remover

Best in Affordability
Check On Amazon

The plant-based ingredients make it environmentally friendly. It will easily remove all kinds of tough stains on bedding or blankets of your infants, children, or even pets. More importantly, it is free of dyes; no chlorine and phosphate are ingredients. People allergic or sensitive to harsh chemicals can easily use them because no chemicals or strong fragrances are present.

Product Pros
  • Made with environmentally friendly plant-based ingredients

  • Safe for sensitive skin and allergies

  • Effective on tough stains from pets

Product Cons
  • May not work on all stain types

Key features/specs
No worries about fabric damage or discoloration as there is no chlorine or any dye
Best to use for removing stains of spit-up, baby food, and milk
If you buy a bundle, there are two sprayer bottles with a stain remover pen
Dreft stain pen is straightforward to use and travel friendly

Top Stain Removers Buying Guide

No matter how careful a person can be while eating, drinking, or doing other work, stains are unavoidable. The only way to avoid stains and make your clothes look new is to use the best stain removers. While shopping, you will see different types of stain remover; for example, some are specifically for surfaces like carpets or bedsheets.

The selection will be dependent on your needs to get the best results. But remember, always pick chlorine-free stain removers as they are gentle on your skin and environment-friendly as well. While shopping, keep the following essential points in mind for making the right purchase:

What Are Two Different Types of Stain Removers?

Generally, there are two types of stain remover: pre-wash applications and in-wash applications. Below you’ll learn more about each and their availability in different forms:

Pre-wash applications

It is a full-strength stain treatment applied directly on the stain before washing it in the washing machine. You can get this in the following forms:

Spray: It makes the application manageable, and you can easily control the amount on each stain.

Foam: Penetrates quickly and deep inside the fabrics to break the stains.

Gel: A thick formula that will stay where you apply, so it gets absorbed inside the stain to remove it.

Stick: Very convenient for treating the on-the-go stains.

Wipes: These are made to remove the stains on contact. You can apply it while wearing the garments, and it is safe for all kinds of dry-cleanable fabrics.

In-wash

This type of stain remover is added along with the detergent in the wash cycle. Some in-wash containers are applied directly to the stains before the wash cycle. These act as a booster to the regular detergent. It is available in the following forms:

Liquid: It is effortless to add and can be applied directly to the stain.

Aerosols: Easily penetrates inside the stain with just a press of a button.

Powder: You can easily add it to a wash cycle or use it for soaking.

Bars: These are portable, lightweight, and can pretreat a stain on contact.

Tablets: Lightweight, portable, and quickly dissolves at any water temperature.

What Are Different Types of Stain Removing Solvents?

Now, we will be looking at the different kinds of solvents used in the stain removers available for different purposes:

Vinegar

It is a natural product and is effective in removing stains. When you use it on wool or synthetics, you should first apply it to a small area to see if any problem happens.

Water

It will be the first line of defense in getting rid of stains. You have to rinse, dab, blot, and repeat the affected fabric or item to remove the stain. You can consider using hot or cold water depending on the fabric you are cleaning. Water itself is not capable of doing any damage.

Hydrogen Peroxide

This solvent is perfect for cleaning rust or bloodstains. It has a bleaching effect, but it will not change the fabric’s color. There will be no discoloration and adequately disinfect the fabric.

Ammonia

It is a valuable and common household cleaning chemical. You will have to dilute it in a spray bottle to use it. Always remember that you should not mix the ammonia with bleach.

Acetone/Mineral Spirits

These play an essential role in removing the stains of paint. Note that these can be harsh when used on synthetics.

Rubbing Alcohol

If you want to remove the stains of dyes, chemicals, and inks, this will be the perfect choice to do the work.

Dish Soap

This is a versatile and mild solvent. It is best in removing grease and condiments stains. To use it, you have to mix it with water.

Detergent

You can use this to scrub out the stains before putting your clothes into the laundry. These have special enzymes which help get rid of stubborn stains.

Bleach

This is effective but harsh as well. Due to its harsh nature, it can be harmful to people with sensitive skin. Always use it as your last option to remove the stain from your white clothes.

What Key Things to Consider When Buying Stain Removers?

There are a few essential things that a person has to keep in mind when buying stain removers:

Know The Fabric Type

When buying the stain remover, you must keep your fabric type in mind. Clothes are made of different kinds of fabric that include synthetic wool, cotton, and silk. There is no way to use one product for all fabric types. For instance, to remove the stain from cotton, you can continuously wash it with hot or cold water and scrub it for better results. However, in the case of delicate silk, it is best to take it to professionals.

By Eco-Friendly Products

When buying the solution for cleaning the stain, ensure ammonia, phosphates, sulfates, or other harmful chemicals or enzymes. Such chemical components are not suitable for the environment. They will be harmful to humans as they might cause reactions or irritation on sensitive skin. Carefully read the labels of the product before buying any product. Remember that the presence of ammonia will be the reason behind discoloration.

How to Remove Stains From Clothes:

Stains can be of many different types, including food, drink blood, grease, ink stains, and many more. Below are some essential tips to remove different kinds of stains from your clothes:

  • Irrespective of the type of stain, you have to act quickly. Don’t let it dry because it will make the removal difficult.
  • Bloating is the key to removing the stains. It would be best never to rub it using a clean white cloth or paper towel.
  • Use cold water first because it will less likely set a stain. Hot water can set protein stains like eggs, blood, and milk.
  • You should check the labels of garments for washing instructions. Some fabric might need dry cleaning only. Moreover, when removing carpet stains, do testing on a small area.
  • You have to be persistent while removing the stain. You might have to repeat the treatment many times in some cases to remove the stains.

Stain Remover FAQs

How long should you allow a stain remover to sit?

Apply the stain remover using your fingers or brush. It would help to let the stain sit for 15 minutes and then wash it. If the stain is dried or old, you will have to mix a solution of oxygen bleach and water. After that, let the garment soak overnight and then wash it.

Are the stain removers harmful?

Some stain remover can be very harmful if contained with ammonia, phosphates, sulfates, and other toxic chemicals. They are detrimental to the environment and humans as well.

Are stains permanent?

Unfortunately, some stains can be permanent. They will become part of the fabric. If you try to remove them, that will only damage your fabric, known as fraying or chafing. Most of the stains get removed by a dry-cleaning machine, and experts have to make an additional effort to remove them.

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Buyer's Report GUIDE Team
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