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The Best Eye Ointments for Dry and Irritated Eyes

Buyer's Report GUIDE Team
Written By Buyer's Report GUIDE Team
Last updated: Feb 20, 2025, 02:25 AM
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Eye ointment

Eye dryness, irritation, or infection can be incredibly uncomfortable and potentially harmful to your vision. Eye ointments offer a soothing and effective solution to these common issues, providing relief and promoting healing. They’re useful as part of a comprehensive treatment plan or as a preventative measure, but since the eyes are one of the most sensitive organs, it’s important to choose a high-quality solution. That’s why we’ve reviewed the best eye ointments available, including the Stye sterile lubricant. This eye ointment is our best overall choice because of its ultra-soothing, ophthalmologist-tested formula. Explore our buying guide and all of these exceptional options to maintain optimal eye health.

View all Contents
  • Buying Guide: Eye Ointments
    • Types of Eye Ointments
    • Factors To Consider Before Buying Eye Ointments
  • People Also Asked
  • Elevating the Shopping Game
  • Contributors
  • Related Reads

Our Top Picks

  • Stye Eye Ointment: Best Overall (Shop Now) →
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  • Refresh P.M. Eye Ointment: Best for Nighttime Use (Shop Now) →
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  • Systane Eye Ointment: Great Value (Shop Now) →
    Read more about this ↓
  • OPTASE Eye Ointment: Best for Cornea Health (Shop Now) →
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  • GenTeal Eye Ointment: Best for Dry Eye Disease (Shop Now) →
    Read more about this ↓

The Best Eye Ointments of 2025

Stye Eye Ointment

Best Overall
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Stye Sterile Lubricant Eye Ointment is the ultimate solution to eye discomfort. This eye ointment features a soothing mix of mineral oil and white petrolatum to provide relief from redness, swelling, burning, and irritation. This dual-action formula provides symptomatic relief and lubricates eyes to prevent the recurrence of styes. It’s also non-irritating, so you can wear it for extended periods without worrying about side effects. 

This eye ointment has been rigorously tested and proven by ophthalmologists to ensure its effectiveness and safety. The convenient, easy-to-use applicator makes applying the product a breeze. Simply apply a small amount of the ointment to the affected area, and let the healing begin! This eye ointment is FSA and HSA-eligible, so you can save on your out-of-pocket expenses. The fast-acting formula and soothing relief help this eye ointment stand at the top of our list.

Product Pros
  • Dual action formula for optimal eye health
  • Ophthalmologist tested for peace of mind
  • Easy to use
  • FSA and HSA eligible
Product Cons
  • Possible allergic reactions for some users

Refresh P.M. Eye Ointment

Best for Nighttime Use
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Are you tired of waking up with dry, irritated eyes? Do you feel like your eyes are burning all the time? The Refresh P.M. Lubricant Eye Ointment is the perfect solution. This nighttime eye treatment helps prevent dry, irritated eyes and can help soothe redness caused by allergies or colds, so you can go about your daily activities without worrying about constantly blinking or rubbing your eyes. 

This product can protect against wind and sun, making it perfect for people who spend a lot of time outdoors or in dusty environments. It’s 100% preservative-free and gentle enough to use around the sensitive skin on your eyelids. This product is suitable for use at nighttime, so you can easily apply it when you’re relaxing in front of the TV or just about to drift off to sleep. 

Product Pros
  • Soothe tired eyes
  • Doubles as an eye protectant
  • Free from harmful preservatives
  • Ideal for nighttime use
Product Cons
  • Can cause temporary blurred vision

Systane Eye Ointment

Great Value
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The Systane Nighttime Eye Ointment can provide relief and protection for your eyes throughout the night. This eye ointment creates a protective barrier with natural ingredients around the eyelids to relieve dry eye symptoms such as inflammation, redness, and watery eyes. 

This unique formula keeps your eyes lubricated and comfortable throughout the night so you can enjoy a restful sleep without any eye-related disruptions. This eye ointment is free from harmful preservatives like m-cresol, chlorocresol, and formaldehyde, ensuring the product is gentle on your eyes and suitable for regular use. This option features a convenient applicator tip, making the application a breeze. 

To apply, simply pull down your lower eyelid and gently squeeze a small amount of the ointment into the pocket between your eye and eyelid. Close your eye and blink a few times to spread the product evenly across the surface of your eye. This eye ointment comes in a pack of three, so you can be sure you’ll have plenty on hand when you need it most.

Product Pros
  • Relieves dry eyes symptoms
  • Lubricates the eyes while you’re sleeping
  • Easy to use
  • Free from harmful preservatives
Product Cons
  • Some customers complain about runny consistency

OPTASE Eye Ointment

Best for Cornea Health
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The OPTASE HYLO Nighttime Eye Ointment effectively relieves itching, burning, redness, and inflammation associated with blepharitis, dry eyes, and styes. Rich in lanolin, white petrolatum, and mineral oil, this eye ointment helps to retain water within the eye’s surface while softening and soothing the delicate skin around the eyes, preventing irritation caused by friction between the eyelids and the eye’s surface. 

With the inclusion of vitamin A, this eye ointment also promotes healthy cornea, supporting overall eye health and helping to maintain good vision. The well-tolerated formula provides several hours of physical retention, ensuring your eyes remain hydrated and protected throughout the night.

The preservative-free formula gives long-lasting protection without compromising your morning vision. The balanced composition of this eye gel is gentle and comfortable on the sensitive skin around the lids and lashes, so you won’t have to deal with irritation or a gritty sensation after applying it. This product has a six-month stability period, so you’ll have plenty of time to use the entire tube before it goes bad.

Product Pros
  • Relieves various eye ailments
  • Well-tolerated formula
  • Phosphate and preservative-free
  • Suitable for all ages
Product Cons
  • Difficult to squeeze

GenTeal Eye Ointment

Best for Dry Eye Disease
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The GenTeal Tears Eye Ointment features a powerful formula to replenish your eyes’ natural moisture so you can say goodbye to even the most persistent dry eye symptoms, such as tingling, itching, and redness. The ointment also works to soothe inflammation and reduce swelling, while the unique lubricating ingredients in this eye ointment help prevent your eyes from sticking together when you expose them to dry air, wind, and cold temperatures. Unlike other eye ointments that can leave a heavy, greasy residue, this eye ointment is lightweight and absorb quickly into your eyes, so you can enjoy instant relief without dealing with a crusty layer over your eyelashes. The best part is that this eye ointment works for all ages.

Product Pros
  • Moisturizes and lubricates eyes effectively
  • Provides severe dry eye symptom relief
  • Protect against common allergens
  • Non-greasy formula
Product Cons
  • Requires frequent reapplication

Buying Guide: Eye Ointments

In this comprehensive buying guide, we’ll provide you with all the information you need to find the perfect solution for your eye care needs. From understanding the different types of eye ointments to knowing what factors to consider before making a purchase, we’ve got you covered.

Types of Eye Ointments

There are several types of eye ointments available on the market, and each option can address a specific eye issue. Knowing the purpose of each option is crucial in selecting the right one for your needs.

Lubricating ointments

These ointments can help provide relief from the dryness, irritation, and discomfort caused by environmental factors, such as wind, dust, or prolonged screen time. They help to maintain the moisture balance in your eyes, keeping them well-hydrated and comfortable.

Antibacterial ointments

If you have an eye infection caused by bacteria, an antibacterial ointment is the way to go. These ointments contain antibiotic agents that help treat bacterial infections, such as conjunctivitis or styes.

Anti-inflammatory ointments

These ointments help to reduce inflammation and swelling in the eyes. They are suitable for conditions like blepharitis, uveitis, or after eye surgery.

Antiviral ointments

Antiviral ointments can help to treat viral eye infections, such as herpes simplex keratitis. They contain antiviral agents that inhibit the growth and spread of the virus.

Antifungal ointments

For fungal eye infections, antifungal ointments are the ideal choice. They contain antifungal agents that help treat infections caused by fungi, such as candida or Aspergillus.

Factors To Consider Before Buying Eye Ointments

Consult an eye care professional

Before purchasing any eye ointment, it’s crucial to consult an eye care professional, such as an optometrist or ophthalmologist. They can help diagnose your eye condition and recommend the appropriate ointment based on your unique needs.

Ingredients

The ingredients in eye ointments can vary widely, so it’s critical to check the label before buying. Look for products that contain vitamins, minerals, and amino acids, such as zinc oxide, lutein, omega-3 fatty acids, and vitamin E. These ingredients help treat your eye condition while soothing itchy or irritated eyes.

Some manufacturers include preservatives in their formula that help keep the ointment from spoiling and prevent the growth of bacteria or fungi in it. These formulas can irritate those with sensitive eyes. In such cases, opt for preservative-free ointments.

Expiration date

Always check the expiration date of the eye ointment before purchasing. Using expired products can lead to eye irritation or infection. Make sure to buy an ointment with a sufficient shelf life and discard it after the expiration date. This step will ensure that you do not use a product that has gone bad.

Storage

Proper storage of your eye ointment is essential to maintain its effectiveness. Most products should be stored at room temperature, away from direct sunlight and heat. Always check the storage instructions on the packaging to ensure you’re storing the ointment correctly.

People Also Asked

How do I apply eye ointments correctly?

To apply an eye ointment, first, wash your hands thoroughly. Tilt your head back slightly and gently pull down your lower eyelid to create a small pocket. Squeeze a small amount of the ointment into the pocket. Close your eyes and gently roll your eyeball around to spread the product. Avoid blinking or rubbing your eye immediately after application.

Can I use eye ointments with contact lenses?

Most eye ointments are not compatible with contact lenses and may cause discomfort or damage to the lenses. Remove your contact lenses before applying the ointment, and wait at least 30 minutes after application before reinserting them. 

How often should I apply my eye ointment?

The frequency of application depends on the specific ointment and the condition you are treating. Some options may require application several times a day, while others may only need to be applied once daily. To avoid any adverse reaction, follow the instructions provided by your healthcare professional or the product packaging. 

What are the side effects of eye ointments?

Side effects of eye ointments can include temporary blurred vision, stinging, burning, redness, or irritation. These side effects are usually mild and should subside shortly after application. If you experience persistent or severe side effects, discontinue use and consult your healthcare professional.

Can I use eye ointments with other eye medications?

If you are using multiple eye medications, consult your healthcare professional for guidance on the proper order of application and wait times between each medication. You should apply eye ointments last. These products can create a barrier that blocks the absorption of other medications.

How should I store my eye ointment?

Store eye ointments in a cool, dry place away from direct sunlight and heat. Keep the container tightly closed when not in use to prevent contamination.

Can I use eye ointments if I have glaucoma?

Consult your healthcare professional before using eye ointments if you have glaucoma because some ingredients may worsen the condition.

What should I do if the eye ointment causes an allergic reaction?

If you experience an allergic reaction to an eye ointment, such as swelling, itching, or difficulty breathing, discontinue use and contact your healthcare professional immediately.

Are there any drug interactions with eye ointments?

Some eye ointments may interact with other medications, including oral medications or other eye drops. Consult your healthcare professional for guidance on potential drug interactions.

Can I use eye ointments if I have a history of herpes simplex eye infections?

Eye ointments are safe if you have a history of herpes simplex eye infections, but you should consult your doctor before using them. If you have a condition that causes recurring eye infections, then it’s best to avoid using eye ointments whenever possible.

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Buyer's Report GUIDE Team
Buyer's Report GUIDE Team
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